Dear Freesurfers,
I am doing an ROI analysis (group comparison) of cortical thickness, and I
have some questions that I could use some help with. Many thanks in advance!
Tudor
1) I used aparcstats2table to extract CT values for structures from the
Destrieux atlas, but I cannot identify some important cortical structures
among the names in that list. For example, I don't see anything
corresponding to the Superior Parietal Lobule, or the Intraparietal Sulcus
(the latter actually does appear but is coupled with another structure,
under the name "lh_S_intrapariet_and_P_trans_thickness")
2) Can the same table (of the average CT of each cortical parcellation) be
extracted using parcellations based on an atlas other than the Destrieux
(e.g. the Harvard-Oxford, or the Julich)?
3) (I can't see whether there's a tutorial for this, as the main FS site
seems to be down at the moment) How can a group comparison of CT be done
inside a given ROI, and in what ways can the ROI be specified? I guess the
command line version of QDEC would produce, in this case, the same
contrasts as QDEC, but within the ROI as opposed to the whole brain
4) How do the results of these two different types of ROI group analyses
differ, and is one of them more "correct" than the other:
A) running the command prompt version of QDEC within the confines of a
certain atlas-defined ROI, and looking at the resulting statistical map
(clusters), as per question 3;
B) extracting the CT values for that ROI for all subjects using
aparcstats2table, and doing t-tests to look for a group difference.
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