Correct, you cannot do a permutation test with continuous variables (or 
with any non-orthogonal design matrix). If you use the --perm-force, it 
will do the permutation test as normal (by randomly swapping the rows), 
but technically the test is not legal. Having said that, I suspect that 
LOTS of people do exactly that.
doug



On 04/04/2013 10:03 AM, Gabriel Gonzalez Escamilla wrote:
>
> Dear Freesurfer experts,
>
>
> I'm having troubles when setting a permutation test, I'm making group 
> comparisons, but I'm introducing the Age, and cortical thickness as 
> niusance variables (as previously recommended).
>
> It seems that permutations only work for orthogonal matrices, does 
> this means that I cannot set any niusance variable?
>
>
> If so, this is telling me that I can run the command with the flag 
> "--perm-force", and I'm wondering, which would be the implications of 
> force to run the permutations with niusance variables?
>
>
> Many thanks in advance,
> Gabriel
>
>
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-- 
Douglas N. Greve, Ph.D.
MGH-NMR Center
gr...@nmr.mgh.harvard.edu
Phone Number: 617-724-2358
Fax: 617-726-7422

Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting
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