I concur. I have seen similar results in primary visual cortex from ~40 
subjects. While fs 5.1 estimated mean thickness in the range of 1.5 to 1.9 in 
V1, fs 5.2 is giving me V1 thickness in the range of 2 to 2.3.

Ritobrato Datta, Ph.D.
Post Doctoral Researcher
Department of Neurology
University of Pennsylvania School of Medicine
3rd Floor, Room 312
3710 Hamilton Walk (Goddard Laboratories)
Philadelphia, PA 19104-6241
email - rida...@mail.med.upenn.edu
 

----- Original Message -----
From: Daniel Yang <yung-jui.y...@yale.edu>
To: freesurfer@nmr.mgh.harvard.edu
Sent: Mon, 18 Mar 2013 17:44:44 -0400 (EDT)
Subject: [Freesurfer] Very different results between 5.1.0 and 5.2.0

Dear FreeSurfer Experts,

I ran FreeSurfer 5.1.0 and FreeSurfer 5.2.0 on identical set of 161 subjects, 
and I'm interested in rh_superior_temporal_sulcus_thickness in particular.

Previously, the mean thickness is 2.24 mm in 5.1.0; now it is 3.28 mm in 5.2.0. 
They are significantly different, t(160) = 56.71.

The correlation between the two versions is r = .33

Is this something possible?? I can't see what went wrong in my procedures.

Thanks!
Daniel

--
Yung-Jui "Daniel" Yang, PhD
Postdoctoral Researcher
Yale Child Study Center
New Haven, CT
(203) 737-5454

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