Hi,
Talairach.xfm is a text file which contains a transformation matrix.
Though there is small numerical difference between two transformation
matrix made using mritotal and the default Talairach registration. The
process of calculation the ICV may amplify this difference since it used
the determinate of the transformation matrix to calculate ICV. The
differences in ICV may depend on how different the numerical values of
the Talairach transformation matrix are.
Best regrards
Knut J
On 12/14/2012 09:06 PM, Eric Cunningham wrote:
Hi,
this link:
http://surfer.nmr.mgh.harvard.edu/fswiki/TalFailV5.1
discusses a solution to bad talairach.xfm transforms, the
-use-mritotal flag.
this link:
http://surfer.nmr.mgh.harvard.edu/fswiki/eTIV
mentions that the talairach.xfm is used to calculate the total
intracranial volume.
is using mritotal likely to result in significantly different
intracranial volumes even if the talairach.xfm does not appear to be
very different when viewed?
thanks much,
-eric
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