Hi Rashmi,
I assume you've read the skullstrip wiki page, but I've included it below 
just in case.

Have you tried different watershed thresholds?  Also, you do not need to 
include the -clean-bm flag every time.  You can run the skullstrip step 
once with the -clean-bm to start from scratch, and the run skullstripping 
again without the -clean-bm flag so that you are performing additional 
skullstripping on the output from the last run.  So something like this:

first:
recon-all -skullstrip -clean-bm -s <subj_ID>
second run:
recon-all -skullstrip -s <subj_ID>

or maybe some variant of those commands where you are also specifying new 
watershed thresholds.

https://surfer.nmr.mgh.harvard.edu/fswiki/FsTutorial/SkullStripFix

Hope that helps.
-Louis

On Tue, 2 Oct 2012, Rashmi Singh wrote:

> Thank you Bruce,
> I certainly understand your point. In my study I am trying to use whole
> brain volume to normalize my volumetrics data. Due to the inclusion of the
> dura into brain, I may get variation in the whole brain volume across
> subjects.
> In addition the current issue is affecting the graymatter/whitematter
> boundary that will also bring variation in the cortical thickness
> measurements.
> That is the reason I was trying to get good skull stripping.
>
> Your suggestions and guidance will help me.
> Thanks,
> Rashmi.
>
>
>
>
> On 10/2/12 2:05 PM, "Bruce Fischl" <fis...@nmr.mgh.harvard.edu> wrote:
>
>> Hi Rashmi
>>
>> getting rid of all the dura without removing any problem is exceedingly
>> difficult (if not impossible). Usually we live with some remaining dura
>> as it doesn't affect the surface placement much.
>>
>> cheers
>> Bruce
>> On Tue, 2 Oct 2012, Rashmi
>> Singh wrote:
>>
>>> Hello experts,
>>>  I am getting skull strip issues with FreeSurfer recon-all runs in every
>>> data.
>>> I ran recon-all on my T1-data and noticed that the skullstrip is not so
>>> good. Almost in every subjects there were  dura included, so I tried the
>>> suggestion of using the flags -skullstrip and -Clean?bm and ?gcut in my
>>> recon-all command line for one subject. Forexmaple:
>>> I ran reconall using the following command lin:
>>> recon-all ?skullstrip first -clean?bm ?gcut ?sAA***.T* -all
>>> -use?mritotal
>>>
>>> The run was complete and I looked at the brainmask.mgz file of the
>>> output.
>>> But I didn't see any correction.
>>> I am attaching the jpg image of the sagittal view of brainmask.nii ( I
>>> converted the mgz file to nii to view tham in afni)
>>> SubjFS: is the image from recon-all run
>>> SubjFS: is the image  from recon-all that was run with
>>> Skullstrip/clean-bm/gcut options included.
>>>
>>> Did I do anything wrong?
>>> Your guidance and suggestion needed.
>>> Thanks,
>>> Rashmi.
>>>
>>>
>>
>>
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