That fact can explain the differences between manual and automatic
segmentations.
But how can I explain the differences just for the left-hippocampus values
in Freesurfer? Comparing percent volume difference between
Freesurfer-Manual and FSL-Manual, the percent is bigger in left-hippocampus
for Freesurfer-Manual. And according to the literature (Morey et al.) the
percent volume difference for Freesurfer-Manual is always smaller than
FSL-Manual as you can see in Fig. 5 of that article.

                        FSL                         Manual
     FreesurferHDHEHDHEHDHE3810.7416983382.601803  3355.53007.537053721
3409.8294672860.18722428682653.533823331      3306.4098913381.8851563025.5
3001.5335835753794.7671472907.55911628802769365134744521.4508974587.515346
36423468404941133794.6383173841.1113483042306640614242

4772.5126714028.94992435703496.548124801      4025.0371153833.112593772.5
351340944224      ??3196.52704.5??      2900.8389382705.713765252624663184
28203607.9960483061.210132749.5258938523591      3694.4012053343.9468022682
2559353035074562.1957574484.21525131563286.541144599
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