Hi Masaya, you are correct. I've put a new version here:
ftp://surfer.nmr.mgh.harvard.edu/transfer/outgoing/flat/greve/mri_segstats.linux
Can you test it out? It also fixes the partial volume computation problem.
thanks!
doug





On 07/06/2012 02:23 PM, Masaya Misaki wrote:
> I've posted a question about a strange behavior of mri_segstats if voxel size 
> isn't 1 mm3 and --pv
> option is used.
>
> I found a reason of this problem in the source code of mri_segstats.c
> (release_5_1_0 branch was checked out from read-only CVS source-code 
> repository)
>
> In mri_segstats.c the return value from 
> MRIvoxelsInLabelWithPartialVolumeEffects is used as the
> number of voxels;
>
> nhits =
>     MRIvoxelsInLabelWithPartialVolumeEffects
>     (seg, pvvol, StatSumTable[n].id, NULL, NULL);
> vol = nhits*voxelvolume;
>
> However, MRIvoxelsInLabelWithPartialVolumeEffects in utils/mri.c returns 
> volume (e.g. volume +=
> vox_vol; or volume += vox_vol * pv;), not the number of voxels.
>
> nhits value is adjusted by voxel volume in mri_segstats.c (vol = 
> nhits*voxelvolume), so that the
> voxelvolume (vox_vol) is multiplied twice.
>
> The volume reported by mri_segstats, therefore, is too small if the voxel 
> volume is less than 1 mm^3
> or too large if the voxel volume is larger than 1 mm3.
>
> Note that this is not a problem when voxel volume is conformed to 1 mm3 
> (default option in recon-all).
>
> I think many of FreeSurfer programs do not support high-resolution (<  1mm3) 
> image without conforming
> to 1 mm3 voxel, but could you fix the problem of mri_segstats? I want to use 
> mri_segstats with
> partial volume correction for high-resolution MRI image.
>
> Thank you,
>
> --Masaya
>
>
> On 06/26/2012 08:40 AM, Masaya Misaki wrote:
>> Hello all,
>>
>> I found volume size reported by mri_segstats is changed very much
>> depending on voxel size when partial volume correction (--pv option) is
>> used. The difference was much larger than that can be explained by the
>> difference of image resolution.
>> (mri_segstats version is 1.75.22 2011/4/27 in FreeSurfer v5.1.0)
>>
>> When I performed segmentation for high-resolution image (voxel size = 0.5
>> mm^3), I found all volumes of segmented regions in aseg.stats was too
>> small; about 8 times smaller than that was estimated from 1mm^3 conformed
>> image.
>>
>> So I tested the effect of voxel size on mri_segstats.
>> At first, recon-all was run with conforming 1mm^3 voxel (default option).
>> Then aseg.mgz and norm.mgz were conformed to small voxel size, and
>> mri_segstats was applied to the conformed files:
>>
>> mri_convert aseg.mgz aseg_cs05.mgz -cs 0.5 ­rt nearest
>> mri_convert norm.mgz norm_cs05.mgz -cs 0.5
>> mri_segstats --seg aseg_cs05.mgz --pv norm_cs05.mgz \
>>     --ctab $FREESURFER_HOME/FreeSurferColorLUT.txt \
>>     --nonempty --excludeid 0 --sum aseg_cs05.stats
>>
>> (these are just for testing the effect of voxel size, not for actual
>> analysis)
>>
>> All volumes reported in aseg_cs05.stats (for 0.5mm^3 voxel) was about 8
>> times smaller than aseg.stats (for 1mm^3 voxel). So the reported volume
>> was scaled with the same ratio as the voxel size. Same effect was observed
>> when voxel size was conformed to larger one (e.g. 1.5mm^3); reported
>> volumes were about 3 times larger than those for 1mm^3-voxel. The number
>> of voxels in the segmented regions (Nvoxels column in aseg.stats) were
>> similar across different voxel sizes while voxel sizes are different.
>>
>> When --pv option was not used, the reported volumes were almost the same
>> across different voxel sizes. So the partial volume correction in
>> mri_segstats seems to depend on voxel size.
>>
>> Can I fix this with some missed options or shouldn't I use --pv option
>> for the image with voxel size other than 1mm^3?
>>
>> thanks,
>>
>>
>> --
>> Masaya Misaki Ph.D.
>>
>>
>
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>

-- 
Douglas N. Greve, Ph.D.
MGH-NMR Center
gr...@nmr.mgh.harvard.edu
Phone Number: 617-724-2358
Fax: 617-726-7422

Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting
FileDrop: www.nmr.mgh.harvard.edu/facility/filedrop/index.html

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