Dear Martin,

the RAS coordinates and voxel to ras transforms are indeed slightly different.
Should I change this and if so, how?

Please find the output of mri_info for each of the two acquisitions at the end
of this email.

Thanks again!
Irene


***********************************************************************************

Volume information for gsTP1/mri/rawavg.mgz
          type: MGH
    dimensions: 256 x 256 x 176
   voxel sizes: 1.0000, 1.0000, 1.0000
          type: FLOAT (3)
           fov: 256.000
           dof: 0
        xstart: -128.0, xend: 128.0
        ystart: -128.0, yend: 128.0
        zstart: -88.0, zend: 88.0
            TR: 0.00 msec, TE: 0.00 msec, TI: 0.00 msec, flip angle: 0.00
degrees
       nframes: 1
       PhEncDir: UNKNOWN
ras xform present
    xform info: x_r =   0.0000, y_r =  -0.0436, z_r =   0.9990, c_r =    -3.5493
              : x_a =  -1.0000, y_a =   0.0000, z_a =   0.0000, c_a =    12.8739
              : x_s =   0.0000, y_s =   0.9990, z_s =   0.0436, c_s =   -16.0490

talairach xfm :
Orientation   : PSR
Primary Slice Direction: sagittal

voxel to ras transform:
                0.0000  -0.0436   0.9990   -85.8823
               -1.0000   0.0000   0.0000   140.8739
                0.0000   0.9990   0.0436  -147.7657
                0.0000   0.0000   0.0000     1.0000

voxel-to-ras determinant -1

ras to voxel transform:
               -0.0000  -1.0000  -0.0000   140.8739
               -0.0436   0.0000   0.9990   143.8789
                0.9990  -0.0000   0.0436    92.2460
                0.0000   0.0000   0.0000     1.0000




***********************************************************************************



Volume information for gsTP2/mri/rawavg.mgz
          type: MGH
    dimensions: 256 x 256 x 176
   voxel sizes: 1.0000, 1.0000, 1.0000
          type: FLOAT (3)
           fov: 256.000
           dof: 0
        xstart: -128.0, xend: 128.0
        ystart: -128.0, yend: 128.0
        zstart: -88.0, zend: 88.0
            TR: 0.00 msec, TE: 0.00 msec, TI: 0.00 msec, flip angle: 0.00
degrees
       nframes: 1
       PhEncDir: UNKNOWN
ras xform present
    xform info: x_r =   0.0000, y_r =   0.0000, z_r =   1.0000, c_r =    -1.5339
              : x_a =  -1.0000, y_a =   0.0000, z_a =   0.0000, c_a =    11.5254
              : x_s =   0.0000, y_s =   1.0000, z_s =   0.0000, c_s =   -19.3390

talairach xfm :
Orientation   : PSR
Primary Slice Direction: sagittal

voxel to ras transform:
                0.0000   0.0000   1.0000   -89.5339
               -1.0000   0.0000   0.0000   139.5254
                0.0000   1.0000   0.0000  -147.3390
                0.0000   0.0000   0.0000     1.0000

voxel-to-ras determinant -1

ras to voxel transform:
               -0.0000  -1.0000  -0.0000   139.5254
               -0.0000  -0.0000   1.0000   147.3390
                1.0000   0.0000   0.0000    89.5339
                0.0000   0.0000   0.0000     1.0000




Selon Martin Reuter <mreu...@nmr.mgh.harvard.edu>:

> Hi Irene,
>
> since those images are not from the longitudinal runs, it really is a
> cross sectional question:
>
> You have two images and the raw average look both similarly noisy, but
> the orig (which is the first image in the recon-all stream) is smoother
> for one than the other.
>
> That means that the conform step (that interpolates the isotropic orig
> from the rawavg) introduces the different smoothing. Not sure why it is
> different.
> You can check (with mri_info) the voxel sizes of your rawavg and the RAS
> coordinates. If they are the same, smoothing should also be the same.
>
> Best, Martin
>
> On Thu, 2011-11-03 at 17:48 +0100, Irene Altarelli wrote:
> > Dear Martin,
> >
> > thanks for your quick reply.
> >
> > I am using version 5.1. I only have two timepoints per subject and I
> > took the snapshots from the independent runs. What bothers me is that
> > the difference is not present in the 001.mgz images, but seems to appear
> > later in the workflow.
> >
> > Thanks again,
> > Irene
> >
> > Le jeudi 03 novembre 2011 à 10:40 -0400, Martin Reuter a écrit :
> > > Hi Irene,
> > >
> > > both images should be smoothed the same. You only have two time points
> > > in each subject? Which FreeSurfer version are you using? And these
> > > images are from the *.long.base directories (or are they from the
> > > independent runs)?
> > >
> > > -Martin
> > >
> > > On Thu, 2011-11-03 at 15:20 +0100, Irene Altarelli wrote:
> > > > Dear Fs experts,
> > > >
> > > > I am running a longitudinal dataset through the longitudinal pipeline,
> > > > and noticed that for one subject, although we kept everything the same
> > > > (sequence, coil etc) the two timepoints' brainmasks look different:
> > > > timepoint one (in the attached snapshot, gs_tp1) looks as if it has
> been
> > > > smoothed, compared to timepoint two (gs_tp2). I have checked some other
> > > > images from this subject, and the same seems to occur for orig.mgz, but
> > > > not for rawavg.mgz.
> > > >
> > > > Any idea on what could be causing the difference would be greatly
> > > > appreciated.
> > > >
> > > > Thanks in advance,
> > > > Irene
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