Derin,

You probably mean the final longitudinal runs (not 'scans').
The longitudinal (-long) runs really should be fine without extra
editing. We have never tried editing them as it was never necessary.
They should be OK, if not there is likely a problem before that needs to
be fixed (e.g. inaccurate registration with the template etc). If that
happens, please let us know.

So I went back and checked a few things:

-brainmask is taken from the base, so if it is wrong, check the base
-talairach.lta also comes from the base and needs to be checked there
-talairach.xfm (only for etiv) is currently taken from the cross
sectionals and needs to be checked there. It might be easier to just
take the ICV from the base-template instead for all time points, ICV
should not change (in adults).
- WM edits are merged in from the base (so editing the longitudinal in
addition should work, but probably not necessary).
- The normalization control points are the only thing I am not really
sure about. We played around with several options (copying it from the
base, or from the cross sectional).  I am not sure what the current
mechanism is, maybe the CP go into the long stream indirectly? We'll
check and update the WIKI.

Best,
Martin


On Wed, 2010-03-10 at 15:16 -0600, Derin Cobia wrote:
> Martin,
> 
> Not to add more to the confusion, but what if the final longitudinal scans 
> are "not fine" and need some editing.  Can they be rerun in the standard way 
> to incorporate edits (e.g., -autorecon2-cp -autorecon3 ... ), or should 
> something different be done?  Will rerunning these edited long scans in the 
> standard fashion disrupt them in some way?  My hunch is that it won't, but I 
> want to make sure.  Thanks.  
> 
> -Derin
> 
> On Mar 10, 2010, at 2:17 PM, Martin Reuter wrote:
> 
> > OK I get it. There was a confusion about adding control points and
> > adding new time points. My answer concerns adding new time points, so
> > you can ignore it. Do not add any edited results as new time points.
> > 
> > Concerning your question see the discussion on this list from Feb 12
> > that treats exactly this topic.
> > 
> > In short:
> > - edit the cross sectionals (you have done that)
> > - run the base and edit the base 
> > - then the longitudinals should be fine
> > 
> > 
> > Martin
> > 
> > On Wed, 2010-03-10 at 13:08 -0600, Guang Zeng wrote:
> >> Hello,  Martin,
> >> 
> >> Thanks a lot for your reply, but I am still not very clear about few
> >> issues.
> >> I think that is because of my unclear description.
> >> 
> >> What happen is:
> >> I have two scans which I want to do longitudinal analysis, however,
> >> when I finish the 
> >> cross-sectional analysis, I found the results are not so good because
> >> of the low contrast 
> >> between white matter and gray matter. I added control points to these
> >> two scans, rerun them. 
> >> The results looks much better now, then I go to the longitudinal
> >> stream. However, when I load the 
> >> longitudinal results, I found the kind of problem happens again (lots
> >> of no-label region in superior frontal). 
> >> So I added control points to the longitudinal results directly, and I
> >> want rerun them. 
> >> 
> >> Based on your reply, I need consider those longitudinal results which
> >> I added control points to as new timepoints, 
> >> rerun them cross-sectionally again, is it correct?
> >> 
> >> Thanks!
> >> Guang
> >> 
> >> 
> >> Here, I just want to add some control points to the FreeSurfer
> >> longitudinal results, 
> >> not new time points. 
> >> 
> >>> Subject: Re: [Freesurfer] modification made to longitudinal results
> >>> From: mreu...@nmr.mgh.harvard.edu
> >>> To: freesurfer...@hotmail.com
> >>> CC: freesurfer@nmr.mgh.harvard.edu
> >>> Date: Thu, 25 Feb 2010 10:33:36 -0500
> >>> 
> >>> Hi Guang,
> >>> 
> >>> Depending on what you do you can choose different routes. Note, for
> >> both
> >>> of these you first need to run the new timepoint cross sectionally
> >> (step
> >>> 1 in the description
> >>> http://surfer.nmr.mgh.harvard.edu/fswiki/LongitudinalProcessing ):
> >>> recon-all -all -s newtpid -i path/to/dicom
> >>> 
> >>> Here are the two options once the cross sectional results are there:
> >>> 
> >>> 1. you have only very few timepoints in the base/template so far (2
> >> or
> >>> 3). In those cases I would recommend to rerun the base and rerun all
> >> the
> >>> longitudinals with the new and more accurate base. The commands are
> >> on
> >>> the Wiki and are the same as usual.
> >>> 
> >>> 2. you have many time points in your base, the additional time point
> >> is
> >>> not likely to change the base much. In that case you can simply
> >> 'patch'
> >>> the base without reprocessing and only run a single longitudinal
> >> run. 
> >>> 
> >>> Let me know if you want to go route 2 because I am writing a script
> >> to
> >>> patch the base (there are a few files that need to be added so that
> >> the
> >>> longitudinal run will go through). If there is demand, I will put
> >>> priority on this and make it available.
> >>> 
> >>> Best, Martin
> >>> 
> >>> On Thu, 2010-02-25 at 09:16 -0600, Guang Zeng wrote:
> >>>> Hi, there,
> >>>> 
> >>>> I need add some control points to the longitudinal results.
> >>>> After adding control points, I need rerun it. which command should
> >> I
> >>>> use?
> >>>> 
> >>>> recon-all -s subj.long.baseid ....
> >>>> or
> >>>> recon-all -long subj baseid ....
> >>>> 
> >>>> 
> >>>> Thanks!
> >>>> Guang
> >>>> 
> >>>> 
> >>>> 
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> >> 
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