its possible to do 1). see the 'ROI Analysis' and 'Group Analysis' tutorials under:
http://surfer.nmr.mgh.harvard.edu/fswiki/FsTutorial although doing this seems like 'double-dipping', or 'circular analysis'. 2) is possible, as it seems like an extension of 1). n. On Sun, 2010-01-31 at 14:20 +0900, Manabu Kubota wrote: > Thank you very much for replying my question. > > I understand how to define ROI, and how to extract data. > > I have a further question. > > Since relatively wide regions are found as significant thickness > reductions in the patient group, > I want to do either > > 1)make a mask where the patient group showed significant reduction, > and using it for further correlational analyses > with clinical variables, to define a "peak vertex" in each region > (in the voxel-based morphometry study in SPM, it is easy to do > correlational group study in the masked region only (not entire > brain), I'm not sure if we can do similar way in freesurfer) > > or > > 2)define ROIs using each region of the significant reduction (I > understand how to do this now), and if the ROI is wide, divide one ROI > into several region (suppose one ROI include both Orbito Frontal and > Superior Frontal, devide it according to the Desikan template), and > search correlation with clinical variables, using SPSS > > I compared cortical thickness between two groups (a control group and > a patient group), and found several areas with significant thickness > reduction in patient group. > > Is it possible to do 1) and 2) with qdec or tksurfer? Or can I do > these from command line? > > > Thanks, > > Manabu Kubota > kubot...@kuhp.kyoto-u.ac.jp > Graduate school of medicine, Kyoto University > > > 2010/1/29 Nick Schmansky <ni...@nmr.mgh.harvard.edu>: > > the qdec tutorial describes how to draw a label on a region, and then > > map that label (roi) back to each subject. from there, aparcstats2table > > can be used to gather that roi data into a table for import into a stats > > program where you perform your analysis. > > > > n. > > > > On Wed, 2010-01-27 at 08:04 +0900, Manabu Kubota wrote: > >> Dear all, > >> > >> Hi, I am a new user of freesurfer, and have a questions on group > >> analysis with qdec. > >> > >> I compared average thickness between two groups (a control group and > >> a patient group). > >> > >> What I am trying to do next is to make a mask where the patient group > >> showed reduction of cortical > >> thickness (for example, p<0.05, FDR), then examine the correlation > >> between clinical scales and cortical thickness in the masked regions, > >> by doing group analysis in the regions (not entire brain). > >> > >> I searched past archives, but couldn't find one. > >> Does anyone know how to do this with qdec ? > >> > >> > >> > >> Thanks for your help, > >> > >> Kind regards > >> > >> > >> > >> Manabu Kubota > >> kubot...@kuhp.kyoto-u.ac.jp > >> Kyoto University > >> _______________________________________________ > >> Freesurfer mailing list > >> Freesurfer@nmr.mgh.harvard.edu > >> https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer > >> > >> > > > > > > _______________________________________________ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
