Thank you very much for replying my question.

I understand how to define ROI, and how to extract data.

I have a further question.

Since relatively wide regions are found as significant thickness
reductions in the patient group,
I want to do either

1)make a mask where the patient group showed significant reduction,
and using it for further correlational analyses
  with clinical variables, to define a "peak vertex" in each region
(in the voxel-based morphometry study in SPM, it is easy to do
correlational group study in the masked region only (not entire
brain), I'm not sure if we can do similar way in freesurfer)

or

2)define ROIs using each region of the significant reduction (I
understand how to do this now), and if the ROI is wide, divide one ROI
into several region (suppose one ROI include both Orbito Frontal and
Superior Frontal, devide it according to the Desikan template), and
search correlation with clinical variables, using SPSS

I compared cortical thickness between two groups (a control group and
a patient group), and found several areas with significant thickness
reduction in patient group.

Is it possible to do 1) and 2) with qdec or tksurfer? Or can I do
these from command line?


Thanks,

Manabu Kubota
kubot...@kuhp.kyoto-u.ac.jp
Graduate school of medicine, Kyoto University


2010/1/29 Nick Schmansky <ni...@nmr.mgh.harvard.edu>:
> the qdec tutorial describes how to draw a label on a region, and then
> map that label (roi) back to each subject. from there, aparcstats2table
> can be used to gather that roi data into a table for import into a stats
> program where you perform your analysis.
>
> n.
>
> On Wed, 2010-01-27 at 08:04 +0900, Manabu Kubota wrote:
>> Dear all,
>>
>> Hi, I am a new user of freesurfer, and have a questions on group
>> analysis with qdec.
>>
>> I compared average thickness between two groups (a control group and
>> a patient group).
>>
>> What I am trying to do next is to make a mask where the patient group
>> showed reduction of cortical
>> thickness (for example, p<0.05, FDR), then examine the correlation
>> between clinical scales and cortical thickness in the masked regions,
>> by doing group analysis in the regions (not entire brain).
>>
>> I searched past archives, but couldn't find one.
>> Does anyone know how to do this with qdec ?
>>
>>
>>
>> Thanks for your help,
>>
>> Kind regards
>>
>>
>>
>> Manabu Kubota
>> kubot...@kuhp.kyoto-u.ac.jp
>> Kyoto University
>> _______________________________________________
>> Freesurfer mailing list
>> Freesurfer@nmr.mgh.harvard.edu
>> https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
>>
>>
>
>
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