Dear FS experts

I had run recon-all -long on two time points and would like to subtract the
cortical thickness maps of the two time points.

Do the two ?h.thickness maps of the different time points are already in the
same space so that they can be directly subtracted in MATLAB?

Or 

Do I have to use mri_surf2surf to register them before I can subtract them?

Do you recommend smoothing the thickness maps?

When looking at T1.mgz with the overlaying aseg the images of the two time
points are not in the same stereotactic space: hence, I would like to known
whether this is also the case for the thickness maps.

Sorry for reposting this question

Thanks
Regards
Jürgen

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Juergen Haenggi
Ph.D. (Dr. des.)
Division Neuropsychology
Institute of Psychology
University of Zurich
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