Hi,

I tried to test FS cortical thickness analysis by using a batch of 10
subjects whose grey matter I manually deleted in the temporal lobes (a
significant part at least). When I compared it to the original 10 images,
little or none changes were significant! I checked the segmentation and I
noticed that the grey/white boundary in the original subjects was too
conservative, hence no changes were detected (at least I believe it is the
only explanantion).

Is it possible to change the segmentation parameters to make it more
"agressive" or am I overlooking something?

Thank you!

Joao Pereira

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