Hi Antonio,

I wouldn't use the wm.mgz for much of anything. It's really just an intermediate step in the creation of the surfaces. In general we trust the ?h.white and ?h.pial surfaces first, then the aseg.mgz for things like hippocampus, ventricles, etc...

Bruce


On Mon, 25 Jun 2007, Gallo, Antonio (NIH/NINDS) [F] wrote:

Hi All,

Upon reviewing subortical segmentations I see that often a mismatch
exists between what appears on the wm.mgz and the color-coded segmented
maps.

Precisely - as an example - in the attached figure you can see that in
the case of left insula WM, part of the tissue was classified as GM (in
brown) in the color-coded segmented map and as WM in the wm.mgz.
Contrariwise, the right temporal-parietal GM cortex part of the tissue
is classified as WM (in green) the color-coded segmented map and as
non-WM in the wm.mgz. The latter occurs in many regions of the brain
without a clear anatomical pattern.



I was wondering if this is just a display issue or it rather reflects
some mismatch in actual tissue classification with consequential errors
in the generated values of thickness and volumes as well?

If so, is there any way I can correct for this?



Thank you in advance,



Antonio





Antonio Gallo, MD

NIB-NINDS-NIH

10 Center Drive

Building 10, Room 5B16

Bethesda, MD, 20892 - USA

ph #: 001-301-402.6391

fax #: 001-301-402.0373

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