Using map and sets:

(defn days-number-maker
  [all-days day-string]
  (let [day-set (set day-string)]
    (map (fn [day]
           (if (day-set day)
             1
             0))
         all-days)))

(defn days-to-numbers
  "Change string like MTTH to (1 1 0 1 0 0 0)"
  [day-string]
  (let [days (clojure.string/replace
               (clojure.string/replace day-string #"TH" "R") #"SU" "N")]
    (days-number-maker "MTWRFSN" days)))

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