Hi Tjaard,

I think these are probably two calcium ions coordinated by water molecules.

Best wishes,
Tomas

On Wed, Sep 10, 2025 at 2:23 PM Tjaard Pijning
<[email protected]> wrote:
>
> Dear community,
>
>
>
> I have a so far unexplained density near two Asp’s and one Asn on the surface 
> of my protein (a bacterial enzyme). It could be connected to the Asp residues 
> but I don’t know of any posttranslational modification (if that’s what it is) 
> that would fit. I’ve put three different views in the attachment with blue 
> 2Fo-Fc contoured at 1.0 sigma, and green/red Fo-Fc at +3.0/-3.0 sigma.
>
>
>
> The crystallization components are PEG 20k, glycerol, MES, BisTrisPropane, 
> NaCl and CaCl2.
>
>
>
> Any help/advice is greatly appreciated!
>
>
>
> With kind regards,
>
> Tjaard
>
>
>
> Dr. Ing. Tjaard Pijning
>
> Biomolecular X-ray Crystallography
> Faculty of Science and Engineering
>
> University of Groningen
>
> Nijenborgh 7, 9747 AG Groningen
>
> The Netherlands
>
> Office 5171.00.70 (Mo-Thu)
>
> Tel +31 6 3192 1948
>
>
>
>
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