Hello everyone, 1) How much change in Tm (ΔTm) in a thermal shift assay is considered to be significant ?
2) A negative ΔTm infers that the compound is making the protein unstable. In such a case, will the co-crystallization be difficult or just impossible or on the contrary it shouldn't matter much? Thanks and best regards, Saif ######################################################################## To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1 This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list hosted by www.jiscmail.ac.uk, terms & conditions are available at https://www.jiscmail.ac.uk/policyandsecurity/
