https://careers-civetta.icims.com/jobs/1395/job
Overview Civetta Therapeutics (Cambridge, MA) is recruiting a Scientist to Senior Scientist level position in Protein Sciences. Civetta is a cutting-edge biotechnology company, backed by Deerfield Management, and recently launched from the Broad Institute and Dana-Farber Cancer Institute (DFCI). Our founders, William Sellers (Broad/DFCI) and Eric Fischer (DFCI), world leaders in genomics and protein biology, launched Civetta with the mission to create a new precision medicine platform targeting “propeller” proteins. We are building a team of talented, dedicated scientists who share our vision and our passion to discover groundbreaking new drugs to treat some of the most difficult diseases, including cancer. If you are a talented life sciences professional who brings energy, passion, and scientific curiosity to the team, we welcome the opportunity to consider you for this important position in our growing company. *The position.* We are seeking an experienced and creative protein biochemist at the Scientist to Senior Scientist level to propel our gene-to-structure (G2S) efforts in Protein Sciences, helping to build world-class platform capabilities in discovering small molecule modulators of beta-propeller proteins, supporting biological discovery and our drug development programs. Responsibilities Key Responsibilities - Provide expertise and insight for construct design and purification protocols for protein production. - Perform purification of challenging beta-propeller proteins to establish robust protocols that can be used internally or transferred to external (CRO) resources as needed. - Specify and procure necessary equipment, enabling technologies and reagents. - Collaborate productively with biochemistry and biophysics colleagues to source protein reagents for assay development targeting beta-propeller proteins and multi-protein complexes. - Make intellectual contributions to all stages of drug discovery and project delivery. Qualifications Qualifications - Ph.D. degree in biochemistry, structural biology or related discipline with 5+ years of industry experience or Master’s/Bachelor’s degree with 10+ years of experience. - Extensive protein biochemistry experience working with challenging proteins and multi-protein complexes. - Experience using specialized purification strategies, such as HIC and protein refolding. - Knowledge of protein structure and experience in the preparation of high-quality, concentrated protein samples for biophysical (SPR, ITC, DSF) and structural studies (NMR, X-ray, Cryo-EM). - Experience balancing CRO and internal resources to solve problems and drive progress. - Exceptional interpersonal and communication skills, and ability to effectively present data within the company and to other stakeholders. - Adept at working effectively within motivated cross-functional scientific teams to deliver project goals within timelines. Civetta Therapeutics provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to religion, race, creed, color, sex, sexual orientation, alienage or citizenship status, national origin, age, marital status, pregnancy, disability, veteran or military status, predisposing genetic characteristics or any other characteristic protected by applicable federal, state or local law. *Notice to Third-Party Recruiters/Staffing Agencies:* Recruitment is managed through Civetta Therapeutics’ Human Resources department. Resumes will only be accepted from staffing agency/recruiters if there is a signed contract in place. Recruiters are requested to not contact our hiring managers or employees directly to inquire about open positions or to present candidates. In the event a staffing agency/third-party recruiter submits a resume without a contract in place, the candidate submitted will be considered unsolicited and treated as if the candidate submitted their resume directly to Civetta, and no fee/payment will be paid. Recruiters interested in working with Civetta Therapeutics can submit their information to cont...@civettatherapeutics.com, and we will contact you if needed. PM18 #LI-DNI ######################################################################## To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1 This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list hosted by www.jiscmail.ac.uk, terms & conditions are available at https://www.jiscmail.ac.uk/policyandsecurity/