Applications are invited for a postdoctoral (research associate) position (18-months in the first instance) in the laboratory of Dr Paul Miller at the Department of Pharmacology, University of Cambridge, beginning from 1st November 2020.
The project will focus on studying the molecular basis of antibody interactions with membrane proteins involved in blood brain barrier transcytosis. This field of research is vital for the establishment of therapeutic antibody delivery to the central nervous system to treat neurological disorders. This is a great opportunity to nurture skills in cryo-EM and/or X-ray crystallography and execute structure-guided antibody engineering, ideal for follow-on academic and biotechnology careers. The lab utilises automated crystallisation robotics and imaging, and new Arctica and Krios microscopes with Falcon 3/K2/K3 direct detectors. More information about the laboratory is available at https://www.phar.cam.ac.uk/research/miller. The applicant will hold a PhD with a solid background in structural biology/biophysics/biochemistry. Advantageous experience includes: protein engineering, production and purification; crystallisation and/or cryo-EM and data processing; phage or yeast display platforms; handling membrane proteins. You must be a careful and methodical worker, paying attention to accuracy and ready to take responsibility as part of a team and willing to work in a collaborative environment. You should be self-motivated and able to organise, perform and analyse experiments with minimal instruction. Application Closing date: 9th August 2020 Project start date: 1st November 2020 For more details and to apply: https://www.jobs.cam.ac.uk/job/26225/ Informal enquiries about the position can be made to Dr Paul Miller (pm...@cam.ac.uk<mailto:pm...@cam.ac.uk>) For enquiries about the online application process please contact Debbie Stanley, phar...@lists.cam.ac.uk ######################################################################## To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1 This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list hosted by www.jiscmail.ac.uk, terms & conditions are available at https://www.jiscmail.ac.uk/policyandsecurity/
