To improve both multiplicity, anomalous signal and dose-proofing from a single crystal - complementing the thread and papers suggested so far and thinking of a strategy that covers low symmetry - the excellent approach introduced at the SLS (Basu et al, http://scripts.iucr.org/cgi-bin/paper?S2059798319003103) to offset chi/kappa at each 180 degree pass done at very low dose per pass is a great strategy. one can exploit one crystal as much as possible by trimming the set later if decay is an issue.
Other than that, multi crystal strategies come in handy with their own downsides, but if reproducible enough crystals are available then that route is a good one, too. an early reference by gumiero et al is great (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3020733/) and one of its latest implementations by ebrahim et al is also great (https://journals.iucr.org/m/issues/2019/04/00/ec5012/). cheers, Jose' === Jose Brandao-Neto MPhil CPhys Senior Beamline Scientist - I04-1 XChem Scientist Diamond Light Source jose.brandao-n...@diamond.ac.uk +44 (0)1235 778506 === ######################################################################## To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1 This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list hosted by www.jiscmail.ac.uk, terms & conditions are available at https://www.jiscmail.ac.uk/policyandsecurity/
