There are many insulin structures with domain shifts. 4ins and 1trz share sequence but have different conformations for one of the molecules.. Eleanor Dodson
On Wed, 9 Oct 2019 at 14:32, Tanner, John J. <tanne...@missouri.edu> wrote: > The same enzyme adopting different quaternary structures is a form of > allosteric regulation. Jaffe's group has described this phenomenon - the > “morpheein" model of allosteric regulation. > > Reviews: > https://www.ncbi.nlm.nih.gov/pubmed/22182754 > https://www.ncbi.nlm.nih.gov/pubmed/16023348 > > > > John J. Tanner, PhD > Professor of Biochemistry and Chemistry > Associate Chair of Biochemistry > University of Missouri > 117 Schweitzer Hall > 503 S. College Avenue > Columbia, MO 65211 > Phone: 573-884-1280 > Email: tanne...@missouri.edu > http://faculty.missouri.edu/~tannerjj/tannergroup/tanner.html > > > > > > On Oct 9, 2019, at 6:14 AM, Gabriela GARCIA RODRIGUEZ < > gabriela.garcia.rodrig...@vub.be <gabriela.garcia.rodrig...@vub.be>> > wrote: > > Dear CCP4BB subscribers, > > I am writing a discussion on extensive quaternary changes between two > different homodimers of the same protein and I would like to ask you for > any examples of your own work/that you know of to include in my analysis. > Basically, any proteins known to exist in two different (or more) > homodimerised states (suffering changes in domain organisation between > states would be even more interesting). > I would greatly appreciate any examples! Thank you for your time and > attention. > > Warm regards, > > Gabriela > ____ > > *Gabriela Garcia Rodriguez* > > *gabriela.garcia.rodrig...@vub.be <gabriela.garcia.rodrig...@vub.be>* > > PhD candidate > > Structural Biology Research Centre (SBRC) > > Vlaams Instituut voor Biotechnologie (VIB) - Vrije Universiteit Brussel > (VUB) > > Pleinlaan 2- 1050 Brussels, Belgium > > > > > > > ------------------------------ > > To unsubscribe from the CCP4BB list, click the following link: > https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=CCP4BB&A=1 > > > > ------------------------------ > > To unsubscribe from the CCP4BB list, click the following link: > https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=CCP4BB&A=1 > ######################################################################## To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=CCP4BB&A=1