See also the IUPAC reccomandations : 

https://goldbook.iupac.org/html/A/A00417.html 

https://goldbook.iupac.org/html/H/H02836.html 

---
Stefano Trapani

Maître de Conférences
http://www.cbs.cnrs.fr/index.php/fr/personnel?PERS=Stefano%20Trapani
-------------------------------------
Centre de Biochimie Structurale (CBS)
29 rue de Navacelles
34090 MONTPELLIER Cedex, France

Tel : +33 (0)4 67 41 77 29
Fax : +33 (0)4 67 41 79 13
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Université de Montpellier
CNRS UMR 5048
INSERM UMR 1054
-------------------------------------

Le 2018-01-31 15:43, F.Xavier Gomis-Rüth a écrit : 

> Hi Johannes, 
> 
> this is normal textbook knowledge, which got perverted over time and 
> misusage. Just check with a serious dictionary like Merrian Webster or 
> 
> even the Wikipedia (see below). 
> 
> Best regards, 
> 
> Xavier 
> 
> https://www.merriam-webster.com/dictionary/apoenzyme [1] 
> 
> https://en.wikibooks.org/wiki/Structural_Biochemistry/Enzyme/Apoenzyme_and_Holoenzyme
>  [2] 
> 
> https://www.biology-online.org/dictionary/Apoenzyme [3] 
> 
> https://en.wikipedia.org/wiki/Enzyme [4] 
> 
> On 31/1/18 15:33, Johannes Cramer wrote: 
> 
>> Dear collegues, 
>> 
>> a while ago, there was a discussion in the board on the term apo-structure 
>> as a way to descibe a native, free, or unbound protein (no ligands). I think 
>> the conclusion was that an apo-form is a halo enzyme lacking a cofactor and 
>> should not be used as a substitute for "unbound". 
>> We were recently asked by a reviewer to change "unbound" to "apo" in a text. 
>> We are weighing our options at the moment. Just comply and change it or 
>> "teach" the reviewer something... 
>> Can anyone share experiences with similar situations? Can anyone point out a 
>> publication on the term? 
>> 
>> Cheers, 
>> Johannes
> 
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Links:
------
[1] https://www.merriam-webster.com/dictionary/apoenzyme
[2]
https://en.wikibooks.org/wiki/Structural_Biochemistry/Enzyme/Apoenzyme_and_Holoenzyme
[3] https://www.biology-online.org/dictionary/Apoenzyme
[4] https://en.wikipedia.org/wiki/Enzyme
[5] http://www.mailscanner.info/

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