No direct experience, but I think that there is some literature supporting increased stability of L-DOPA drug formulations with ascorbate.
- John On Thu, Jul 3, 2014 at 1:34 PM, Keller, Jacob <kell...@janelia.hhmi.org> wrote: > Dear Crystallographers, > > Does anyone have experience with co-crystallization of a protein with L-Dopa? > In my hands, the L-Dopa degrades in water to a dark solution within 10 > minutes. I am thinking of trying some reductants and metal chelation, but a > verified successful formula would be much appreciated, and preferably it > would be without going into a glove box. > > Jacob Keller > > ******************************************* > Jacob Pearson Keller, PhD > Looger Lab/HHMI Janelia Farms Research Campus > 19700 Helix Dr, Ashburn, VA 20147 > email: kell...@janelia.hhmi.org > *******************************************
