Dear Almudena, if you follow the recommendations given in the "Difficult datasets" article on XDSwiki, your problem would have a good chance to be solved.
best wishes, Kay On Mon, 19 May 2014 18:18:46 +0200, Almudena Ponce Salvatierra <maps.fa...@gmail.com> wrote: >Dear all, > >I am looking for some suggestions here. I have lately collected some >datasets but the spots are very very weak... it is very difficult to >process them. At times it looks like XDS is stalled or at times it just >says that it can not interpret the lattice parameters... also while running >integrate I have such a message after each range of images: > >!!! WARNING !!! REFINEMENT DID NOT CONVERGE > LAST CORRECTION SHIFT WAS 9.1E-03 (should be < 1.0E-03) > >I guess this is not good at all. And I wonder what to do? Is there any info >that I can get out from these data at all? or rather not? > >I wonder if the problem is to find the spots, I have tried with HKL2000 and >it can't even find enough of them for indexing. > >Any ideas are welcome. > >Best wishes, > >Almudena. > >-- >Almudena Ponce-Salvatierra >Macromolecular crystallography and Nucleic acid chemistry >Max Planck Institute for Biophysical Chemistry >Am Fassberg 11 37077 Göttingen >Germany >
