Hi ,
      Seems to me that crystal packing is not good thats why mosaic
diffraction, this might be due to DNA so you can increase diffraction
quality by using 1 or 2 nucleotide sticky end  DNA for crystallization
which can help in crystal packing .

Vandna Kukshal
Postdoctral Research Associate
Dept. Biochemistry and Molecular Biophysics
Washington University School of Medicine
660 S. Euclid, Campus Box 8231
St. Louis, MO 63110

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