"What is the best procedure to use for weak anomalous signal" That opens up the can of worms which I'm happy to jump into. We've had very good success in the years 2003-2009 with shelx for finding sites (sometimes more than 10000 trials) then force feeding them to sharp for phase improvement. We should also say most of the times in particular in the more difficult cases xds made the difference in detectable anomalous signal.
And no we still have not published this. With we I mean Marc Robien and myself during our SGPP times. Jürgen ...................... Jürgen Bosch Johns Hopkins Bloomberg School of Public Health Department of Biochemistry & Molecular Biology Johns Hopkins Malaria Research Institute 615 North Wolfe Street, W8708 Baltimore, MD 21205 Phone: +1-410-614-4742 Lab: +1-410-614-4894 Fax: +1-410-955-3655 http://lupo.jhsph.edu On Jan 14, 2013, at 3:13, "James Holton" <jmhol...@lbl.gov> wrote: > What is the best procedure to use for weak anomalous signal