Sorry for this ccp4 unrelated question.
We recently have a protein that a multicoil program (http://groups.csail.mit.edu/cb/multicoil/cgi-bin/multicoil.cgi/cgi-bin/multicoil
) predicts to have very high probability for dimer and trimer. Their
scores are close to 0.4 and 0.6 for lengths of more than 60 amino
acids. However, two constructs that cover this region have
demonstrated monomers in solutions by Multiangle light scattering?!
For the same question, we could not get any response from this program
manager therefore we turn to ccp4 for help. We wonder whether some of
you might have similar experience. Thank you in advance.
Sincerely,
Aidong
