Thanks Roger,
that worked perfectly!
I'll try and have fun with aline now.
ciao,
s

On May 25, 2010, at 7:56 PM, Roger Dodd wrote:

> Hi there,
> 
> I just got this working a couple of days ago under Mac OS X 10.6.3. I 
> manually compiled and installed Perl-Tk from CPAN. Steps taken:
> 
> 1. Download and ungzip / untar: 
> http://search.cpan.org/CPAN/authors/id/S/SR/SREZIC/Tk-804.028_501.tar.gz (the 
> newer -503 version didn't work)
> 2. Change into the directory
> 3. Execute perl Makefile.PL
> 4. make
> 5. make test
> 6. sudo make install
> 
> Hopefully that should get things working.
> 
> Cheers,
> 
> Roger
> 
> On 25 May 2010 17:50, Sebastiano Pasqualato 
> <sebastiano.pasqual...@ifom-ieo-campus.it> wrote:
> Hi there,
> I remember a friend of mine showing me Aline, and it looked very nice.
> However, I can't make it work on my MacBook Pro (Mac OS X 10.6.3).
> With respect to the instruction I found on the website, I had to change the 
> export lines to be added to the .bashrc in order not to get error messages.
> That's how I added the path info:
> 
> export ALINEHOME='/sw64/share/xtal/aline_011208'
> export PATH=$PATH:$ALINEHOME/bin
> 
> however, I still get an error while trying to run aline:
> 
> s...@host005:~> aline
> Can't locate Tk.pm in @INC (@INC contains: /sw64/lib/perl5 
> /sw64/lib/perl5/darwin /Library/Perl/Updates/5.10.0 
> /System/Library/Perl/5.10.0/darwin-thread-multi-2level 
> /System/Library/Perl/5.10.0 /Library/Perl/5.10.0/darwin-thread-multi-2level 
> /Library/Perl/5.10.0 /Network/Library/Perl/5.10.0/darwin-thread-multi-2level 
> /Network/Library/Perl/5.10.0 /Network/Library/Perl 
> /System/Library/Perl/Extras/5.10.0/darwin-thread-multi-2level 
> /System/Library/Perl/Extras/5.10.0 .) at 
> /sw64/share/xtal/aline_011208/bin/aline line 37.
> BEGIN failed--compilation aborted at /sw64/share/xtal/aline_011208/bin/aline 
> line 37.
> s...@host005:~>
> 
> I even tried with the
> 
> perl -MCPAN -e 'install Tk'
> 
> command, as suggested by the website, but nothing changed.
> 
> Any idea of what's wrong here?
> Thanks a lot for the tips,
> ciao
> s
> 
> On May 25, 2010, at 5:47 AM, Charlie Bond wrote:
> 
> > Hi Victor,
> > Thanks for recommending ALINE.
> >
> > It is not exactly true that development has stopped. It is just glacially 
> > slow as funding for such utilities is not easily obtained!
> >
> > Recommendations for improvements (to improve that potential) are 
> > well-received and a keen user can write their own plug-ins to achieve new 
> > functionality.
> >
> > Cheers,
> > Charlie
> >
> > Victor Alves wrote:
> >> Hi Mohd
> >> You can also check: ALINE (An Extensible WYSIWYG Protein Sequence 
> >> Alignment Editor for Publication Quality Figures)
> >> http://crystal.bcs.uwa.edu.au/px/charlie/software/aline/
> >> It’s quite nice and has a lot of potential, although unfortunately it 
> >> seems that development of the software as stopped  :-(
> >> Cheers
> >> Victor Alves
> >>   *From:* CCP4 bulletin board [mailto:ccp...@jiscmail.ac.uk] *On Behalf Of 
> >> *Salameh, Mohd A., Ph.D.
> >> *Sent:* sexta-feira, 21 de Maio de 2010 16:11
> >> *To:* CCP4BB@JISCMAIL.AC.UK
> >> *Subject:* [ccp4bb] Alignment software
> >> Dear All,
> >> I’m trying to prepare an alignment figure of 2 proteins that highlight 
> >> conserved and similar residues and probably secondary structures; I will 
> >> greatly appreciate it if anybody can recommend a software that I can use. 
> >> Thanks, Mohd
> >
> > --
> > Charlie Bond
> > Professorial Fellow
> > University of Western Australia
> > School of Biomedical, Biomolecular and Chemical Sciences
> > M310
> > 35 Stirling Highway
> > Crawley WA 6009
> > Australia
> > charles.b...@uwa.edu.au
> > +61 8 6488 4406
> 
> 
> --
> Sebastiano Pasqualato, PhD
> IFOM-IEO Campus
> Dipartimento di Oncologia Sperimentale
> Istituto Europeo di Oncologia
> via Adamello, 16
> 20139 - Milano
> Italy
> 
> tel +39 02 9437 5094
> fax +39 02 9437 5990
> 
> 
> 
> -- 
> Roger B. Dodd, PhD.
> Cambridge Institute for Medical Research
> Wellcome Trust/MRC Building
> Hills Road
> Cambridge
> CB2 0XY
> UK


-- 
Sebastiano Pasqualato, PhD
IFOM-IEO Campus
Dipartimento di Oncologia Sperimentale
Istituto Europeo di Oncologia
via Adamello, 16
20139 - Milano
Italy

tel +39 02 9437 5094
fax +39 02 9437 5990

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