Hi there, I remember a friend of mine showing me Aline, and it looked very nice. However, I can't make it work on my MacBook Pro (Mac OS X 10.6.3). With respect to the instruction I found on the website, I had to change the export lines to be added to the .bashrc in order not to get error messages. That's how I added the path info:
export ALINEHOME='/sw64/share/xtal/aline_011208' export PATH=$PATH:$ALINEHOME/bin however, I still get an error while trying to run aline: s...@host005:~> aline Can't locate Tk.pm in @INC (@INC contains: /sw64/lib/perl5 /sw64/lib/perl5/darwin /Library/Perl/Updates/5.10.0 /System/Library/Perl/5.10.0/darwin-thread-multi-2level /System/Library/Perl/5.10.0 /Library/Perl/5.10.0/darwin-thread-multi-2level /Library/Perl/5.10.0 /Network/Library/Perl/5.10.0/darwin-thread-multi-2level /Network/Library/Perl/5.10.0 /Network/Library/Perl /System/Library/Perl/Extras/5.10.0/darwin-thread-multi-2level /System/Library/Perl/Extras/5.10.0 .) at /sw64/share/xtal/aline_011208/bin/aline line 37. BEGIN failed--compilation aborted at /sw64/share/xtal/aline_011208/bin/aline line 37. s...@host005:~> I even tried with the perl -MCPAN -e 'install Tk' command, as suggested by the website, but nothing changed. Any idea of what's wrong here? Thanks a lot for the tips, ciao s On May 25, 2010, at 5:47 AM, Charlie Bond wrote: > Hi Victor, > Thanks for recommending ALINE. > > It is not exactly true that development has stopped. It is just glacially > slow as funding for such utilities is not easily obtained! > > Recommendations for improvements (to improve that potential) are > well-received and a keen user can write their own plug-ins to achieve new > functionality. > > Cheers, > Charlie > > Victor Alves wrote: >> Hi Mohd >> You can also check: ALINE (An Extensible WYSIWYG Protein Sequence Alignment >> Editor for Publication Quality Figures) >> http://crystal.bcs.uwa.edu.au/px/charlie/software/aline/ >> It’s quite nice and has a lot of potential, although unfortunately it seems >> that development of the software as stopped :-( >> Cheers >> Victor Alves >> *From:* CCP4 bulletin board [mailto:ccp...@jiscmail.ac.uk] *On Behalf Of >> *Salameh, Mohd A., Ph.D. >> *Sent:* sexta-feira, 21 de Maio de 2010 16:11 >> *To:* CCP4BB@JISCMAIL.AC.UK >> *Subject:* [ccp4bb] Alignment software >> Dear All, >> I’m trying to prepare an alignment figure of 2 proteins that highlight >> conserved and similar residues and probably secondary structures; I will >> greatly appreciate it if anybody can recommend a software that I can use. >> Thanks, Mohd > > -- > Charlie Bond > Professorial Fellow > University of Western Australia > School of Biomedical, Biomolecular and Chemical Sciences > M310 > 35 Stirling Highway > Crawley WA 6009 > Australia > charles.b...@uwa.edu.au > +61 8 6488 4406 -- Sebastiano Pasqualato, PhD IFOM-IEO Campus Dipartimento di Oncologia Sperimentale Istituto Europeo di Oncologia via Adamello, 16 20139 - Milano Italy tel +39 02 9437 5094 fax +39 02 9437 5990
