I'm looking for references where people have tried to at least vaguely quantify the energetics of stacking the guanidinium groups of two R's. I'm looking at 3 cases in protein-protein interfaces, and in each one there's a D or E adjacent, which presumably helps with the charge-charge repulsion. Hints as to where to start reading? thanks in advance, Phoebe
==================================================== Phoebe A. Rice Assoc. Prof., Dept. of Biochemistry & Molecular Biology The University of Chicago phone 773 834 1723 http://bmb.bsd.uchicago.edu/Faculty_and_Research/01_Faculty/01_Faculty_Alphabetically.php?faculty_id=123 RNA is really nifty DNA is over fifty We have put them both in one book Please do take a really good look http://www.rsc.org/shop/books/2008/9780854042722.asp