Protein Production Core in the Enzyme Function Initiative ---------------------------------------------------------
We are looking to recruit individuals with extensive experience in molecular biology, protein purification, crystallization and automation to join the Protein Production Core of the newly established NIH-funded Enzyme Function Initiative (EFI). The goal of the EFI is to develop a general sequence/structure-based strategy for facilitating the discovery of in vitro enzymatic activities and in vivo physiological functions of uncharacterized enzymes discovered in genome projects. This goal will be accomplished by integrating informatics, structural biology and computational chemistry with enzymology, genetics and metabolomics. The EFI involves 13 investigators at 8 academic institutions.
The Protein Production Core is located within the Macromolecular Therapeutics Development Facility at the Albert Einstein College Medicine and is fully equipped to pursue all aspects of state-of-the-art structural genomics. The Protein Production Core exploits extensive automation and an active program focused on the development of novel protein expression/purification strategies, utilizing both prokaryotic and eukaryotic hosts.
Interested candidates should provide a CV and arrange for two letters of support to be forwarded to Dr. Ron Seidel at rsei...@aecom.yu.edu.
