Jacob
Have you seen the Crystal Catcher system, developed in Japan? http://adsabs.harvard.edu/abs/2008APExp...1c7002K Some of us saw it at a recent IUCr meeting, but I don't know anyone who has tried it with their own proteins Patrick -- For information and discussion about protein crystallization and automation, please join our bulletin board at http://groups-beta.google.com/group/oryx_group?hl=en <http://groups-beta.google.com/group/oryx_group?hl=en> patr...@douglas.co.uk <mailto:patr...@douglas.co.uk> Douglas Instruments Ltd. DouglasHouse, EastGarston, Hungerford, Berkshire, RG177HD, UK Directors: Peter Baldock, Patrick Shaw Stewart http://www.douglas.co.uk/ <http://www.douglas.co.uk/> Tel: 44 (0) 148-864-9090 US toll-free 1-877-225-2034 Regd. England 2177994, VAT Reg. GB 480 7371 36 From: CCP4 bulletin board [mailto:ccp...@jiscmail.ac.uk] On Behalf Of Jacob Keller Sent: 26 March 2009 19:43 To: CCP4BB@JISCMAIL.AC.UK Subject: [ccp4bb] Crystal vacuum cleaner Dear Crystallographers, Has anybody ever heard of mounting crystals in tiny crystal-sized capillaries, such as are pulled by patch-pipet machines, or those used in microfluidics? The material could be either glass or plastic, and one could have some method of continuous positive or negative pressure, perhaps through a hole in the crystal cap. Anyway, once safely inside the tiny capilary, one could freeze it at leisure, without concern for evaporation. It would really make harvesting easy--just vacuum up the crystal, then plop in LiqN2/propane as per usual. I guess it could also really be done with appropriate modification of a micro-manipulator. Jacob ******************************************* Jacob Pearson Keller Northwestern University Medical Scientist Training Program Dallos Laboratory F. Searle 1-240 2240 Campus Drive Evanston IL 60208 lab: 847.491.2438 cel: 773.608.9185 email: j-kell...@northwestern.edu *******************************************
