[ccp4bb] artificial dimerization modules

[Arnon Lavie]

This is not strictly a crystallography question, but I imagine (and 
hope) that some of you would be able to advise me. In short, I would 
like to add to the N-terminal part of my construct a sequence that will 
promote dimerization of the molecule.

Background: I am working on a large protein that is built from multiple 
domains. I am interested in the structure of some of the more C-terminal 
domains. Obviously, I do not have well diffracting crystals at this 
point (and hence this post). N-terminal to the domains of interest is a 
dimerization domain. I would like to mimic the dimerization induced by 
this domain by adding as short as possible a sequence. Moreover, I would 
like to try both a parallel and an anti-parallel dimerization motif.

Would you know of an appropriate short sequence (e.g. one that makes a 
helix which dimerizes), or of a very small domain that I could add to my 
construct?

Thanks.

Arnon