BS"D
Hello All,
One can find in many organic chemistry textbooks statements about
how SN2 reactions on carbon atoms in cyclohexyl rings are not
favoured because of hindrance from the axial substituents (even
hydrogen). Unfortunately, I'm having trouble (say via google)
finding some references for this. Perhaps I'm not defining my search
properly. In any case, is someone familiar with some references for
this?
Thanks
Harry
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Harry M. Greenblatt
Staff Scientist
Dept of Structural Biology [EMAIL PROTECTED]
Weizmann Institute of Science Phone: 972-8-934-3625
Rehovot, 76100 Facsimile: 972-8-934-4159
Israel