The AD9361 has internal compensation for DC offset and I/Q imbalance. 

Make sure that you’re running with a recent system image for E312.  

Sent from my iPhone

> On Jan 5, 2018, at 5:18 PM, Xingjian Chen via USRP-users 
> <usrp-users@lists.ettus.com> wrote:
> 
> Hi,
> 
> Is there any way for E312 to self-calibrate? I found there is IQ imbalance in 
> amplitude and dc offset showing in the recorded signal's real and imaginary 
> part. But it seems that its daughter board is not supported for 
> self-calibration. Any idea to solve this? Thank you very much. 
> 
> 
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