I wonder what for the silver was in.

Marshall

David Bearrow wrote:

> I found the following study to be of interest:
>
> Alleviation of silver toxicity by selenite in the rat in relation to tissue
> glutathione peroxidase
>
> PA Wagner, WG Hoekstra and HE Ganther
>
> Dietary Se (0.5 ppm Se supplied as sodium selenite to a casein-based diet
> containing 0.02 ppm Se and lacking in vitamin E) prevented the growth
> depression observed in rats receiving 76 ppm Ag in the water supply and
> markedly improved growth and survival of those given 751 ppm Ag. The Ag
> concentration of liver and possibly of kidney was increased by Se. Liver
> glutathione peroxidase activities from rats fed 0.5 ppm Se and given 76 and
> 751 ppm Ag for 52 days in their water were, respectively, 30% and 4% of
> those from control rats fed 0.5 ppmSe without Ag. In rats fed a diet,
> adequate in vitamin E (100 IU/kg) and Se (0.5 ppm as sodium selenite),
> administration of 751 ppm Ag in the water for 15 wk reduced liver GSH-Px
> activity to 5% of that from control rats receiving no Ag. GSH-Px activity
> of erythrocytes and kidney was decreased by Ag to 37% and 38%,
> respectively, of control values. It is concluded that in vivo
> administration of Ag dramatically decreased liver GSH-Px in rats fed
> Se-supplemented diets with or without vitamin E. Furthermore, supplemental
> Se (0.5 ppm) prevented the growth depression and mortality caused by Ag in
> rats fed a diet lacking vitamin E, while increasing the Ag concentration of
> liver and kidney.
>
> Proceedings of the Society for Experimental Biology and Medicine, Vol 148,
> 1106-1110, Copyright © 1975 by Society for Experimental Biology and Medicine
>
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> ¦              David Bearrow             ¦
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