Dear Susanna,
in addition to MD calculations I suggest you to perform a check on your
mutated protein. Circular dichroism is a simple technique that allows to
monitor the global fold of your protein.
Mutating a residue may affect the folding and this seems an
underestimated problem in the li
Hi Susanna,
As you can see, pymol allows you to mutate residues. However, in order to
assess their influence, you should most likely run MD simulations on both
the wild type protein and mutant(s) and compare.
Kind regards,
Sorin
On Tue, Apr 12, 2022, 5:35 PM susanna pagni wrote:
> Hello,
>
>
Hello,
I am quite new to PyMOL. I would like to assess how an amino acid change might
affect the protein structure. I used the Wizard Mutagenesis to change the amino
acid of interest but don’t know how I can see how the protein structure is
affected by the mutation.
Can you please help me with
