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Dear NONMEM users,
as beginners in NONMEM we have the following questions:
- What is the meaning of "DEL" and "W" (in the subroutine $ERROR)?
- What is the meaning of "TOL" and when should it be used?
- Assumed we need to use $DES, is this possible only with NONMEM version 7 or
can we use
Dear NONMEM Users,
we try to start a NONMEM run. An error report tells us that:
"FILE=Allrecords.txt this option is already been specified"
Do you have an idea how could we avoid this error?
Thanks a lot and many greetings from still rainy Cologne.
Paola and Lisa<>
Paola & Lisa,
Please see responses interspersed below.
Best regards from snowy Buffalo,
Luann Phillips
Director PK/PD
Cognigen Corporation
(716) 633-3463 ext 236
di Gion, Paola wrote:
Dear NONMEM users,
as beginners in NONMEM we have the following questions:
- What is the meaning
Paola,
On 31/03/2011 3:02 p.m., di Gion, Paola wrote:
Dear NONMEM users,
as beginners in NONMEM we have the following questions:
- What is the meaning of "DEL" and "W" (in the subroutine $ERROR)?
They are sort of like a virus that is spread by copying and pasting from
old control streams pa
Hi Paola and Lisa,
On 3/31/2011 3:47 PM, di Gion, Paola wrote:
> "FILE=Allrecords.txt this option is already been specified"
> Do you have an idea how could we avoid this error?
As you've already noticed, nmusers is full of people just waiting to
help you. :-) In order to make this easier for t
I’m assuming that you may have specified the AllRecords.txt twice in your
$TABLE statement
$TABLE … FILE … FILE=AllRecords.txt
Could be a possibility.
Please send a control stream for a better diagnosis.
Matt.
From: owner-nmus...@globomaxnm.com [mailto:owner-nmus...@globomaxnm.com] On
Beha
Paola,
I agree with Nick that there may be little use for the DEL and W variables.
The standard coding may be something like:
$ERROR
IPRED = F
IRES = DV-IPRED
W = THETA(#)*F
DEL = 0
IF(W.EQ.0) DEL = 1
IWRES = IRES/(W+DEL)
Y = F+EPS(1)*W
The W represents the “weight” of the error model. In the
Dear Matt and all,
In the code you gave, DEL is a protection when F=0 as it may be in a lag-time
model, not only for IWRES but also for the model as such. You can’t have a
proportional error model with a prediction of zero. Add an absolute error
component or switch from a lag to a transit co
