[NMusers] repetitive parameter estimation

2011-03-21 Thread kehua wu
Hi, We have a data file with 250,000 simulated patients, and we want to estimate a parameter in NONMEM using a different set of 50 patients at a time (5,000 replicates, but not bootstrapping). Is there an easy way that anybody knows to automatically repeat the parameter estimation while substitut

Re: [NMusers] repetitive parameter estimation

2011-03-21 Thread Nick Holford
Kehua, You dont describe how you got the 250,000 simulated patients but the simplest way to achieve what you want is to create a data file template with 50 patients then use NONMEM to simulate then estimate with 1000 subproblems. e.g. $PROB simest $DATA my50patients.dat $INPUT ID TIME etc $S

RE: [NMusers] repetitive parameter estimation

2011-03-21 Thread Bill Bachman
See the documentation for $DATA. Set up multiple problems within a single control file. Use the RECORDS= option to select the number of data records for 50 patients, use the NOREWIND option so that for each problem, the data for the next 50 patients. _ From: owner-nmus...@globomaxnm.com

Re: [NMusers] GPU port for NONMEM

2011-03-21 Thread chee ng
Hi Mark, Xavier and all,   Thank you for sharing the information.  Someone pointed me to this interesting discussion about the GPU and NLME in NMuser group.   Recently, I developed a prototype of GPU-based QRPEM (Quassi-Random Parameteric EM) algorithm  in a single laptop computer equipped with

RE: [NMusers] GPU port for NONMEM

2011-03-21 Thread Amr Ragab
Hey Chee, Its good to hear that the conversation didn't fall off the radar and thank you for your efforts in GPU. Looks like we have been working in parallel (no pun intended) to get NONMEM GPU friendly. I am on the GPU here, I am not familiar with the FX3800M, on our side I have a NVIDIA FX5800 a

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