See the documentation for $DATA. Set up multiple problems within a single control file. Use the RECORDS= option to select the number of data records for 50 patients, use the NOREWIND option so that for each problem, the data for the next 50 patients.
_____ From: owner-nmus...@globomaxnm.com [mailto:owner-nmus...@globomaxnm.com] On Behalf Of kehua wu Sent: Monday, March 21, 2011 2:55 PM To: nmusers@globomaxnm.com Subject: [NMusers] repetitive parameter estimation Hi, We have a data file with 250,000 simulated patients, and we want to estimate a parameter in NONMEM using a different set of 50 patients at a time (5,000 replicates, but not bootstrapping). Is there an easy way that anybody knows to automatically repeat the parameter estimation while substituting the new data each time? Thanks, Kehua
