...@globomaxnm.com] on behalf of
Bauer, Robert [robert.ba...@iconplc.com]
Sent: Tuesday, December 22, 2015 1:40 PM
To: Bill Gillespie
Cc: nmusers@globomaxnm.com
Subject: RE: [NMusers] BAYES method and initial estimate bounds
Bill:
Yes, and when that happens, the execution path is difficult to anticipate.
Robert
c.com<http://www.iconplc.com>
From: Bill Gillespie [mailto:bgillespies...@gmail.com]
Sent: Tuesday, December 22, 2015 11:25 AM
To: Bauer, Robert
Cc: nmusers@globomaxnm.com
Subject: Re: [NMusers] BAYES method and initial estimate bounds
Hi Bob,
Thanks for the reply. On investigating further I see this hap
UNCONDITIONAL
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> Robert J. Bauer, Ph.D.
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> Vice President, Pharmacometrics R&D
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> ICON Early Phase
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> Office: (215) 616-6428
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> *From:* owner-nmus...@globomaxn
Of Bill Gillespie
Sent: Tuesday, December 22, 2015 8:14 AM
To: nmusers@globomaxnm.com
Subject: [NMusers] BAYES method and initial estimate bounds
Hi all,
If bounds are specified in the $THETA statements for initial estimates, what,
if any, effect do they have when the BAYES method is used?
I initia
Hi all,
If bounds are specified in the $THETA statements for initial estimates,
what, if any, effect do they have when the BAYES method is used?
I initially thought they might work in conjunction with the prior
specifications to implement truncated priors. However that does not seem to
be true be
