[Freesurfer] contrast matrix of 2 factors (2x4 groups)

2009-10-06 Thread Stefan Brauns
Hi all, I am trying to examine the interaction of 2 factors (2 x 4 groups) and have difficulties to find the right contrast matrix for mri_glmfit. We have patients and controls at four different aquisition sites and want to know if the changes (i.e. thickness) between patients and controls are equ

[Freesurfer] mri_glm-sim

2009-10-06 Thread Martin Kavec
I wonder how log does it ususally take to complete cluster-wise correction for multiple comparisons using mri_glm-sim. I have a group analysis of 19 subjects with 1 continuous and 1 discrete factor (two levels) and the mri_glm-sim is running now for about 4 days. Is there any way to track the p

[Freesurfer] skull strip...

2009-10-06 Thread Gonzalo Rojas
Hi: The command: recon-all -skullstrip -wsthresh 35 -clean-bm -no-wsgcaatlas -s only runs the skullstrip procedure ?... Which is the "clone" tool ?... Sincerely, -- Gonzalo Rojas Costa Department of Radiology Las Condes Clinic Lo Fontecilla 441, Las Condes, Santiago, Chile. Te

[Freesurfer] QDEC

2009-10-06 Thread Jose Soares
Hi all, I am working with QDEC and I would like to know if it is possible to do subcortical structures (e.g. hippocampus, amygdala, putamen) analyses in qdec?? I only have cortical structures mapped in my analyses. Thanks for the help, Miguel.

[Freesurfer] group contrast with different slice thicknesses/xyz dimensions/orientations

2009-10-06 Thread James Root
I am planning an analysis using freesurfer to compare 2 groups. The SPGRs that will be used vary in regard to slice thickness (from 0.86 to 1.5 in each axis), number of slices acquired (100-256), and orientation (axial; coronal) due to the fact that these were collected over a number of years on t

Re: [Freesurfer] QDEC

2009-10-06 Thread Nick Schmansky
Miguel, No, not yet. Sorry. You can use the command-line tool mri_glmfit to do the analysis though. Also, its pretty easy to export a table of the data and use a plain stats tools. See: http://surfer.nmr.mgh.harvard.edu/fswiki/FsTutorial/AnatomicalROI Nick On Tue, 2009-10-06 at 08:45 -0700,

Re: [Freesurfer] skull strip...

2009-10-06 Thread Bruce Fischl
the clone tool is useful for copying parts of the unstripped volume back into the stripped one if parts of the brain are incorrectly removed (it's part of tkmedit) Bruce On Tue, 6 Oct 2009, Gonzalo Rojas wrote: > Hi: > > The command: > recon-all -skullstrip -wsthresh 35 -clean-bm -no-wsgc

Re: [Freesurfer] Freesurfer auto verse manual segmentation for hippocampus

2009-10-06 Thread Bruce Fischl
Hi Aize, what is your definition of hippocampus? Does it coincide with our's? Is fimbria included? Alveus? Bruce On Tue, 6 Oct 2009, caoaize wrote: Hello Bruce, We did manual and freesurfer auto segmentation on hippocampus for 39 subjects. I attached the comparison plot here. As seen in

Re: [Freesurfer] group contrast with different slice thicknesses/xyz dimensions/orientations

2009-10-06 Thread Bruce Fischl
Hi James, it certainly can. If one group had all one scan type and another all a different one then you wouldn't be able to tell if the effects you find are due to the group membership or the scan differences. cheers, Bruce On Tue, 6 Oct 2009, James Root wrote: > I am planning an analysis usi

Re: [Freesurfer] optseq2 help: DPSD and jitter

2009-10-06 Thread Douglas N Greve
I don't know what "two samples" refers to. doug Asaf Kaftory wrote: > Hey Doug - first of all, thanks for the reply. second - > > 1. I'm afraid i didn't get the explanation. what is the FIR, and what > does it mean "two samples in the FIR" ? > > 2. ok, thanks. isn't it strange though? how do res

Re: [Freesurfer] contrast matrix of 2 factors (2x4 groups)

2009-10-06 Thread Douglas N Greve
It would be the same as your 2nd matrix with the right four columns negated. doug Stefan Brauns wrote: > Hi all, > > I am trying to examine the interaction of 2 factors (2 x 4 groups) > and have difficulties to find the right contrast matrix for mri_glmfit. > > We have patients and controls at f

Re: [Freesurfer] tkregister2 questions

2009-10-06 Thread Douglas N Greve
It means that you don't have permission to write into that directory. The images look a little off. What kind of scanner are you using? doug Weisinger, Brian (NIH/OD) [E] wrote: > When I try to use tkregister2 I get this message, how do I go about changing > not being able to save the changes I

[Freesurfer] How to use mris_register

2009-10-06 Thread Xiaojing Long
Hi, all, I am new to FreeSurfer world. I am trying to do the surface-based registration using FreeSurfer. I found a tool called mris_register, which is defined as a command registering a surface to an average surface template(or another single-subject's surface). But I don't understand how to use

Re: [Freesurfer] group contrast with different slice thicknesses/xyz dimensions/orientations

2009-10-06 Thread Douglas N Greve
Does each group have a mix of parameters or does each group have its own set of parameters. If the latter, then it is a real problem. doug Bruce Fischl wrote: > Hi James, > > it certainly can. If one group had all one scan type and another all a > different one then you wouldn't be able to tell

Re: [Freesurfer] How to use mris_register

2009-10-06 Thread Douglas N Greve
The surface-based registration is usually done as part of recon-all (which runs mris_register with all the appropriate arguments). You trying to do something different? doug Xiaojing Long wrote: > Hi, all, > > I am new to FreeSurfer world. I am trying to do the surface-based > registration us

Re: [Freesurfer] How to use mris_register

2009-10-06 Thread Bruce Fischl
Hi Xiaojing, the inputs are an individual subject sphere created with mris_sphere, and statistics in an atlas coordinate system, usually stored in a tif file that we supply. cheers, Bruce On Tue, 6 Oct 2009, Xiaojing Long wrote: > Hi, all, > > I am new to FreeSurfer world. I am trying to do

Re: [Freesurfer] How to use mris_register

2009-10-06 Thread Xiaojing Long
Hi, Bruce, Thank you so much for your help. Now my understanding on 'mris_register' is that: 1. I need to construct the 'xx.sphere' for all my inputs; 2. For the 'source.sphere', I also need to provide 'source.curv' and 'source.sulc'. 3. For the 'target.sphere', I need to have a statistical f

Re: [Freesurfer] How to use mris_register

2009-10-06 Thread Bruce Fischl
yes, that is correct. All that info is generated as a matter of course during recon-all. Bruce On Tue, 6 Oct 2009, Xiaojing Long wrote: Hi, Bruce, Thank you so much for your help. Now my understanding on 'mris_register' is that£º 1. I need to construct the 'xx.sphere' for all my inputs; 2. F

Re: [Freesurfer] How to use mris_register

2009-10-06 Thread Xiaojing Long
Hi, Douglas, Thank you so much for your help. I once ran the recon-all for my subjects and I got the 'xx.sphere.reg's. Are these results the warped sphere surfaces to the atlas? I am trying to register the wm surface of subject1 to surface of subject2, so I am seeking for help to use 'mris_regis

Re: [Freesurfer] How to use mris_register

2009-10-06 Thread Bruce Fischl
there is -1 switch you can give mris_register to directly register one surface to another, but in our experience using the atlas statistics and the measures of cross-subject variability stabilizes the whole procedure On Tue, 6 Oct 2009, Xiaojing Long wrote: > Hi, Douglas, > > Thank you so much

Re: [Freesurfer] How to use mris_register

2009-10-06 Thread Xiaojing Long
Thank you all so much. I will first try to figure out how 'mris_register' works for registering a subject to the atlas. Then think about my problem. Best, Xiaojing 2009/10/6 Bruce Fischl > there is -1 switch you can give mris_register to directly register one > surface to another, but in ou

[Freesurfer] tkmedit "save main volume as.." option...

2009-10-06 Thread Gonzalo Rojas
Hi: I do all the steps of the "Manual Editing" process that appears in http://surfer.nmr.mgh.harvard.edu/fswiki/FsTutorial/SkullStripFix, but the "save main volume as.." option appears in gray (off)... Why ?... I thought it might be a access permission related issue, but it was not... Si

Re: [Freesurfer] tkregister2 questions

2009-10-06 Thread Weisinger, Brian (NIH/OD) [E]
Would it be a problem to skip this step by using the -notal-check or would that mess the results up too much? On 10/6/09 2:03 PM, "Douglas N Greve" wrote: That might be a problem as (I think) our target is made from 3T data, and the contrast might be different. Pratap, is your anatomical data

Re: [Freesurfer] tkregister2 questions

2009-10-06 Thread Douglas N Greve
Depends on what you want to do with it. It probably won't affect the surface/subcortical analysis. But if you try to report tal coordinates for this subject or try to make an average subject using this subject (and/or other subjects that have a bad tal), then the coordinates will be off. doug

Re: [Freesurfer] tkregister2 questions

2009-10-06 Thread Weisinger, Brian (NIH/OD) [E]
So if I wanted to do the longitudinal stream it would be important to fix these then. Is it possible to do this longitudinal stream if the scanner was a 1.5t and therefore the talairach will be off since the target was 3t and the contrast may be off? On 10/6/09 2:23 PM, "Douglas N Greve" wrot

Re: [Freesurfer] tkregister2 questions

2009-10-06 Thread Douglas N Greve
I don't think it will affect the longitudinal stream, but Martin would know more. Weisinger, Brian (NIH/OD) [E] wrote: > So if I wanted to do the longitudinal stream it would be important to fix > these then. Is it possible to do this longitudinal stream if the scanner was > a 1.5t and therefor

Re: [Freesurfer] optseq2 help: DPSD and jitter

2009-10-06 Thread Asaf Kaftory
Hello list, attached is my first post plus my new questions underneath every paragraph. thanks. > > > > I'm new to optseq, and would like your help with the following issues: > > 1. What exactly does DPSD mean? and why does the TR has to be an > integer of it? > > Doug: Delta Post-Stimulus Dela

Re: [Freesurfer] optseq2 help: DPSD and jitter

2009-10-06 Thread Douglas N Greve
FIR stands for "Finite Impulse Response". You define a time window that brackets your stimulus response then compute the average response at each time point inside the window. Eg, the window might start at stimulus onset (psd=0) and be sampled at each TR (eg, 2 sec) until the end of the window

Re: [Freesurfer] FW: tkregister2 questions

2009-10-06 Thread Martin Reuter
Hi Brian, yes it looks like this is slightly too small. A little stretching does not hurt. The talairach transform from the base is used for all the longitudinal runs, so if it is wrong, this will have an influence. In your case, however, I think it might not be a big problem (as the difference is

[Freesurfer] mris_expand

2009-10-06 Thread Don Hagler
Bruce recently wrote that you could run mris_expand like this: mris_expand -t lh.white 0.5 lh.graymid I found that didn't work, but this did: mris_expand -thickness lh.white 0.5 lh.graymid I am using version 4.4. By the way, is there a way to increase the resolution of the surfaces before cre

Re: [Freesurfer] mris_expand

2009-10-06 Thread Bruce Fischl
oops, you're right. -t does something else that is irrelevant. There is code around for supersampling the surface, but it's not integrated into anything yet. I assume you have the source so you should be able to try it out if you want. cheers, Bruce On Tue, 6 Oct 2009, Don Hagler wrote: > >

[Freesurfer] QA Cortex

2009-10-06 Thread Jeff Sadino
Hello, I want to do a quality check of the cortex for 140 subjects, as far as making sure it is segmented correctly. What files are the best ones to load up to check this in fs 3? If I load the aseg.mgz file up in tkmedit and look at the cortical regions, there are some regions where there is no

Re: [Freesurfer] QA Cortex

2009-10-06 Thread Bruce Fischl
Hi Jeff, just for the cortex I would run: tkmedit $subject norm.mgz lh.white -aux-surface rh.white -aux wm.mgz and check to see if the gray/white and pial surfaces are accurate. Don't worry about the cortex labels in the aseg - it's not what we use cheers Bruce On Tue, 6 Oct 2009, Jeff Sadino

[Freesurfer] Please let me know whether the source code is open.

2009-10-06 Thread Youngsang Cho
Dear all, I am a PH. D. student at KAIST in KOREA. I am researching cortical surface analysis. So I'd like to anaylize the source code, and it seems that the source code is open. However, I couldn't find any link or cvs ID in the freesurfer wiki. Please let me know whether the code is really open