Re: [Freesurfer] Ris: eTIV question

2016-02-23 Thread angela . favaro
yes, I agree. I will explore both thank you! Angela > > That is, going back to your earlier post, I personally don’t find it all > that interesting whether a given brain area is atrophic relative to head > size, especially in the situation where many regions are atrophic (i.e., > global atrophy).

Re: [Freesurfer] Ris: eTIV question

2016-02-22 Thread Harms, Michael
That is, going back to your earlier post, I personally don’t find it all that interesting whether a given brain area is atrophic relative to head size, especially in the situation where many regions are atrophic (i.e., global atrophy). I’m more interested in knowing whether the atrophy in a given

Re: [Freesurfer] Ris: eTIV question

2016-02-22 Thread Harms, Michael
Even assuming one had a true measure of TIV, if you get meaningfully different results when using TIV vs. brain size as a covariate, isn’t that a rather important thing to point out? cheers, -MH -- Michael Harms, Ph.D. --- Conte Center for

Re: [Freesurfer] Ris: eTIV question

2016-02-22 Thread Bruce Fischl
Hi Angela yes, although if the eTIV is (incorrectly) correlated with atrophy you may be removing some of your effect (and slightly reducing your power) cheers Bruce On Mon, 22 Feb 2016, angela.fav...@unipd.it wrote: Hi Bruce, this is true, but I noticed that many papers used TIV as a covar

Re: [Freesurfer] Ris: eTIV question

2016-02-22 Thread angela . favaro
Hi Bruce, this is true, but I noticed that many papers used TIV as a covariate. In addition, in my samples (both pathological and healthy) there is a moderate positive correlation between gyrification and TIV (and brain volume). For the hemispheric overall gyrification index the correlation is 0.3-

Re: [Freesurfer] Ris: eTIV question

2016-02-22 Thread Bruce Fischl
Hi Angela gyrification is the ratio of areas and hence dimensionless, so I would think it wouldn't be much affected by TIV. cheers Bruce On Sun, 21 Feb 2016, angela.fav...@unipd.it wrote: In the case of a gyrification analysis, does correction for total brain volume make sense? Angela In

[Freesurfer] Ris: eTIV question

2016-02-21 Thread angela.fav...@unipd.it
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