Re: [Freesurfer] Multicenter studies

2017-05-09 Thread Douglas Greve
For the interaction it would be 0.5 -0.5 -0.5 0.5 On 5/9/17 8:32 AM, Laura Ferrero Montes wrote: > >Thank you for the information. I just want to be sure if I have > understood it properly. >If I had two groups and two sites, my design matrix would be like: > > GroupDescriptorFile 1 > Cl

Re: [Freesurfer] Multicenter studies

2017-05-09 Thread Laura Ferrero Montes
Thank you for the information. I just want to be sure if I have understood it properly. If I had two groups and two sites, my design matrix would be like: GroupDescriptorFile 1 Class PatientsGroup1 Class PatientsGroup2 Class ControlsGroup1 Class ControlsGroup2 If I want to test for the

Re: [Freesurfer] Multicenter studies

2017-05-08 Thread Douglas N Greve
You should make sure to have a balanced design (ie, approx the same pats and cons at each site). Then include site as a regressor, ie, if you had two groups and two sites, you would have four regressors. You could then test for the effect of group, the effect of site, and the interaction. If t

[Freesurfer] Multicenter studies

2017-05-08 Thread Laura Ferrero Montes
Dear FS team, In case I have data from different centers and I would like to do a group analysis between Patients and Controls, how different centers effects could be regressed out? Should I have to analyze if there is an interaction between center and group? I have seen examples of continu