Re: [Freesurfer] Generating Surfaces Meshes

2020-04-24 Thread Bruce Fischl
Hi Jonah no, I don't think that would be very accurate. In our cortical surface stream we do partial volume modeling in the surface deformation so that the surface settles at the right point between gray/white and gray/csf. We never wrote anything comparable for the aseg structs like hippocamp

Re: [Freesurfer] Generating Surfaces Meshes

2020-04-24 Thread Peter, Jonah
Hi Bruce, I'm interested in generating meshes for the whole brain,and individual regions of the prefrontal cortex and the hippocampus. It seems that freesurfer doesn't generate meshes with physical volumes corrected for partial volume effects, but instead performs an a posteriori calculation that

Re: [Freesurfer] Generating Surfaces Meshes

2020-04-24 Thread Bruce Fischl
Hi Jonah I'm not positive I understand, but I doubt partial volume effects are isotropic given the geometric complexity of a lot of brain structures. Maybe the easiest thing for you to do is to use something like SAMSEG in the upcoming V7 and try deforming the surface to pass through the p=0.5

Re: [Freesurfer] Generating Surfaces Meshes

2020-04-23 Thread Peter, Jonah
Hi Bruce, The issue is that I want the surface mesh itself to reflect the correct (partial volume corrected) volume as I will be simulating the passage of high energy particles through it. Do you think it would suffice to take the (smoothed) mesh and simply scale its volume in an application like

Re: [Freesurfer] Generating Surfaces Meshes

2020-04-23 Thread Bruce Fischl
HI Jonah it depends how you compute volume. mris_volume for example will compute the volume of the interior without any partial volume correction. And yes, I would expect you want to smooth the surface a bit. You might try the Taubin smoothing built into freeview as it won't shrink the surfac

Re: [Freesurfer] Generating Surfaces Meshes

2020-04-23 Thread Peter, Jonah
Hi Bruce, I tried mri_tessellate which worked well in that the surface seems to follow the aseg projections exactly. Does the volume of this mesh account for partial volume effects? Also, is there a need to run mri_pretess or some sort of smoothing procedure? For reference, what I am trying to do

Re: [Freesurfer] Generating Surfaces Meshes

2020-04-23 Thread Bruce Fischl
no, they are definitely not negligible. It depends on structure geometry, but I bet for something like the hippocampus a large fraction of voxels in it are partial volumed. You can use mri_mc or mri_tessellate to generate a mesh. It will be closed but may not have a simple topology On Thu, 2

Re: [Freesurfer] Generating Surfaces Meshes

2020-04-23 Thread Peter, Jonah
Hi all, Thanks for the response. I'm familiar with partial volume effects within the context of PET imaging, but wouldn't you expect these effects to be negligible in MRI for structures on the order of mm? With respect to the mesh type, I'd like to get closed meshes for each segmentation/parcella

Re: [Freesurfer] Generating Surfaces Meshes

2020-04-23 Thread Bruce Fischl
Hi Jonah when we compute volumes we typically use a partial-volume model, which we have found improves accuracy and repeatability. That may be the source of your discrepancy cheers Bruce On Wed, 22 Apr 2020, Peter, Jonah wrote: Hello, I'm trying to generate surface meshes for different brai

Re: [Freesurfer] Generating Surfaces Meshes

2020-04-23 Thread Tim Schäfer
External Email - Use Caution Could you clarify what kind of meshes you are working with? Are the meshes you are working with plane-like (parts of the pial surface), or are they closed (e.g., generating from running marching cubes on a set of cortex voxels)? Also what is your int

[Freesurfer] Generating Surfaces Meshes

2020-04-22 Thread Peter, Jonah
Hello, I'm trying to generate surface meshes for different brain regions that can be imported into a software like MeshLab or Blender (i.e. .STL, .PLY, .OBJ, etc.). I ran recon-all on my T1 images, and the parcellation/segmentation looks fine. However, I noticed that when I imported this data into