Hi Bruce,

I tried mri_tessellate which worked well in that the surface seems to
follow the aseg projections exactly. Does the volume of this mesh account
for partial volume effects? Also, is there a need to run mri_pretess or
some sort of smoothing procedure?

For reference, what I am trying to do is import these surface meshes into a
Geant4 simulation for proton therapy, and want to make sure I'm using as
realistic geometry as possible. Ideally I'd be able to generate a mesh for
the whole brain as well as individual segmentations.

Thanks again for your help,
Jonah

On Thu, Apr 23, 2020 at 5:50 PM Bruce Fischl <fis...@nmr.mgh.harvard.edu>
wrote:

> no, they are definitely not negligible. It depends on structure geometry,
> but I bet for something like the hippocampus a large fraction of voxels in
> it are partial volumed.
>
> You can use mri_mc or mri_tessellate to generate a mesh. It will be closed
> but may not have a simple topology
>
> On Thu, 23 Apr 2020, Peter, Jonah
> wrote:
>
> > Hi all,
> > Thanks for the response. I'm familiar with partial volume effects within
> the context of PET imaging, but
> > wouldn't you expect these effects to be negligible in MRI for structures
> on the order of mm?
> >
> > With respect to the mesh type, I'd like to get closed meshes for each
> segmentation/parcellation.
> >
> > Is there a way to do this in freesurfer?
> >
> > On Thu, Apr 23, 2020 at 10:44 AM Bruce Fischl <
> fis...@nmr.mgh.harvard.edu> wrote:
> >       Hi Jonah
> >
> >       when we compute volumes we typically use a partial-volume model,
> which we
> >       have found improves accuracy and repeatability. That may be the
> source of
> >       your discrepancy
> >
> >       cheers
> >       Bruce
> >       On Wed, 22 Apr 2020, Peter, Jonah wrote:
> >
> >       > Hello,
> >       > I'm trying to generate surface meshes for different brain
> regions that can
> >       > be imported into a software like MeshLab or Blender (i.e. .STL,
> .PLY, .OBJ,
> >       > etc.). I ran recon-all on my T1 images, and the
> parcellation/segmentation
> >       > looks fine. However, I noticed that when I imported this data
> into 3DSlicer,
> >       > the volumes of these regions did not match the volumes in the
> aseg.stats
> >       > file. In some cases, the differences were quite substantial. I
> tried
> >       > removing all smoothing filters in 3DSlicer but the outcome was
> the same.
> >       >
> >       > Do you know what could be going wrong here? Alternatively, is
> there an
> >       > easier way to generate surface meshes from the aparc or aseg
> atlases?
> >       >
> >       > I'm using the ICBM 2009c Nonlinear Asymmetric
> >       > template (http://nist.mni.mcgill.ca/?p=904) as a generic brain
> volume
> >       > (though alternative suggestions are welcome).
> >       >
> >       > Thanks!
> >       > Jonah
> >       >
> >       > --
> >       > Jonah PeterGraduate Student in The Biophysics ProgramHarvard
> University
> >       > P: 646-306-0848
> >       > E: jonahpe...@g.harvard.edu
> >       >
> >       >_______________________________________________
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> >
> >
> >
> > --
> > Jonah PeterGraduate Student in The Biophysics ProgramHarvard University
> > P: 646-306-0848
> > E: jonahpe...@g.harvard.edu
> >
> >_______________________________________________
> Freesurfer mailing list
> Freesurfer@nmr.mgh.harvard.edu
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-- 
Jonah Peter
Graduate Student in The Biophysics Program
Harvard University
P: 646-306-0848
E: jonahpe...@g.harvard.edu
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