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Dear all,
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Hi Experts,
I have a problem to see the residue information on COOT if I click on residue
info and place the curser their its just blink and disappear as I want to
reduce some occupancy manually and it did not work but for water and the other
stuff its work completely fine but not for the amino
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Hi everyone
I was working on a protein complex where one protein binds with the other
protein majorly based on its surface charge. The protein complex yields
nice crystals but does not diffract. Additionally the crystals used to
dissolve within the drop when allowed for incubation both at 18 deg
I don't know about solving this in Coot but would using a plain text editor on
the PDB file be a way to work around the issue? There is also the
spreadsheet-style PDB editor in i2??
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Original Message
On 27 Jul 2021, 15:21, Afshan Begum wrote:
> Hi E
Have you tried including a small amount of chymotrypsin? There were quite a few
papers about this technique 10-15 years ago. It worked for one of our proteins,
but I'm not sure about its success with complexes.
Good luck, Jon.C.
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Original Message
On
Hey Dr Afshan,
You can also check the tab menu: Measure>Go to Atoms. There you can enter
the residue number. The particular residue will be selected, and centred.
Thereafter go to the Measure tab, and click residue info. A dialogue box
will pop open, and there you may edit the values. I hope this
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Hey Rakesh,
Such are the questions that every crystallographer faces in his/her
everyday life. I am not sure if there is any straight forward answer. So
make voyages !
Terese Bergfors mentioned in her famous book, "Protein crystallization" a
case where a Scientist from Umea Uni got the diffraction
Hi Rakesh,
The first question I have is: why do the crystals dissolve after some time? Did
you use a ligand for crystallization that might be turned-over by the protein?
What I would do first in your case is to try to find a stabilizing buffer.
Since you have obtained nice-looking crystals, ther
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