Hi:
Sorry for the same posting in here as well but I thought may be some of
you might have encountered the same problem but may not be subscribing
to sharp list.
I am trying run sharp/autoSHARP on a mac (os x 10.4) using the guven
example file: krel1-SAD.0
I am getting an error at the CAD as
Dear Robbie, List,
This thread is steadily diverging. Apologies for my contribution to its
diversification.
> Who knows what they did to the maps in terms of (unwarrented) density
> modefication to make them look cleaner?
>
> The advantage of the EDS is that it is impartial and
> uniform. The
Dear Nicholas,
Yes we are diverging, but you make a few important and valid points. So
let's diverge some more...
I fully agree that validation tools should not tell people how to do
science. That would kill free thought and lead to circularity in the
results. A typical example is the question wh
I just scrapped most of my answer, Robbie was quicker, and I guess
Gerard is on holiday ;-)
As 'honorary Dutch' though here are my two cents.
It is only fair that a well-informed and well-educated human
being can do a better job than a fixed-frozen automated procedure.
This is exactly the w
Those Greeks again ...
> Finally, validation tools are not there to pass judgement. They are
> tools to be used by depositors, referees, and users alike, to help them
> make a better informed interpretation of crystallographic *models*.
> Servers like EDS and PDB_REDO must be seen in that light
Not sure if in any of the 112 posts regarding either the retraction
theme or 'was 12 retraction' theme did mention, that after all despite
good or as good as possible refinement of the structure, the goal is
still to describe as accurately as possible the biological system
using crystallogr
On Dec 13, 2009, at 11:00 AM, Jürgen Bosch wrote:
If you can't confirm your structure by solid biochemical or
biophysical methods what conclusions should you draw ?
Don't you wish it worked the other way in that every time someone had
a biochemical, physiological, or genetic result, they wo
*Post-Doctoral Researcher. Structure and Function of Membrane Protein
Complexes*.
We seek a motivated individual to join our laboratory in the Department of
Biological Chemistry at the University of California in Los Angeles. We are
interested in studying the mechanisms of protein folding/transloc
Morning all
Apologies for the simple question. I have a structure I would like to
solve using molecular replacement. I am a bit confused by the patterson
peaks. There appears to be a large non-origin peak (although it is
apparently symmetry-related to the origin?). Does this mean that there
is
