Hi Eike,
I wouldn't necessarily let the morphology deter you. While working on my
PhD, a colleague collected beautiful data from hollow crystals.
If the crystals collapse while looping, is it possible for you to perform
"micro-surgery" on the crystal so that you only have a single face?
Sometimes
Dear all,
Is there a documented case of a structure determination from a hollow crystal?
We have the unfortunate situation that a protein only crystallizes as a hollow
tube, where the inside is filled with solvent, which ruins the diffraction
patterns.
I was often confronted with similar situa