Thanks, Artem!
PDE2A also uses three domains to form a homodimmer. However, without the
catalytic domain, the GAF B domain swings out. This is an excellent
example for the restrictions set by the multidomain context.
Anyone knows other examples?
Thanks a lot!
> PDE2 full length versus domain only
PDE2 full length versus domain only structures, I think.
Artem
On Thu, Jan 12, 2012 at 10:03 AM, Qiang Chen wrote:
> Hi,
>
> I'm working on a multi-domain protein which uses three domains to form
> homodimer, and the full-length structure is available. We have solved the
> structure of one bindi
Hi,
I'm working on a multi-domain protein which uses three domains to form
homodimer, and the full-length structure is available. We have solved the
structure of one binding domain alone and found its homo-binding mode is
totally different from that of the full-length protein.
Do you know example
